The President announced in December 2009 that the criteria for initiating ART in the South African public sector would be increased from 200 cells/µl to 350 cells/µl which means that more HIV-infected people will be able to get treatment.
For those who have to plan and budget resources, it is important to find out as much as possible about the costs of providing HIV health care and how these change over time. However, few studies have investigated these costs, particularly those incurred before an individual starts taking ART.
Recent research has analysed the direct costs of treating more than 100,000 HIV-infected adults enrolled in a private HIV care programme in South Africa from 3 years before they started ART until up to 5 years after ART initiation. Within this programme, individuals began to receive ART when their CD4 cell count fell below 350 cells/ml. The ART initiation criteria used in the private sector study setting is thus the same as the recently adjusted criterion in the public sector.
Findings from the study have policy implications:
Results suggest that starting ART once the patient is severely immune compromised (e.g. at CD4<50 cells/µl) is bad for the patient and bad for the budget. Recent policy announcements about when to start ART implies that more patients in South Africa will get treatment, and there could be a reduction in the early costs of ART programmes. However, starting ART earlier is likely to lead to overall cost increases in the long run as patients could live for longer.
Invest in systems to monitor ART adherence and implement effective interventions if patients do not take their drugs regularly.
1) Who’s to say that the investment in “monitor[ing]” equipment, and the upkeep thereof, will not actually lead not to a reduction in “later” costs, but an increase? Sounds like a bit of a wager, too much current costing/projecting expenses absent to really vote on Part II, above. But, Re Part I, yes, it does read as though early ART’s could reasonably “lead to overall cost increases in the long run as patients could live for longer” — but of course that raises the ethical issue/question of, “but isn’t longer life the aim?” Careful balance is key, here. This terminology seems to be lacking.
This blog is a summary of a published journal article, for a broader and more detailed discussion of the terminology and key findings, please refer to http://www.plosmedicine.org. The title was: Early and Late Direct Costs in a Southern African Antiretroviral Treatment Programme: A Retrospective Cohort Analysis.